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Ibuprofen (Brufen)
Ibuprofen Information
Ibuprofen is a kind of drug that
belongs to the group of medicines called non-steroidal anti-inflammatory drugs
or NSAIDs. Ibuprofen functions in the body by blocking the action of a
substance in the body called cyclo-oxygenase that is involve in the production
of various chemicals in the body such as prostaglandins that causes
inflammation, pain, and swelling. In other words, Ibuprofen is used to relieve
pain and inflammation.
NSAIDs medicines such as Ibuprofen
reduce inflammation caused by the body’s own immune system. Ibuprofen is an
effective painkiller. Ibuprofen relieves pain such as muscular aches and pains,
headache, backache, period pains, rheumatic pains, neuralgia, and dental
pains. Ibuprofen also reduces the symptoms of colds and flu.
Ibuprofen Indications
Ibuprofen is indicated to treat fever,
inflammations, and mild to moderate pains.
Ibuprofen Warnings
Ibuprofen belongs to the FDA pregnancy
category B for first two trimesters and FDA pregnancy category D for third
trimesters. Consult your doctor first before taking Ibuprofen if you are
pregnant or planning to be pregnant. Ibuprofen may cause severe defects to an
unborn baby. It is always safe to use Ibuprofen during pregnancy if you discuss
with your doctor the benefits and the risks that Ibuprofen may cause to the
mother and to the unborn baby.
Studies show that Ibuprofen passes into
the breast milk, but in such small quantities, it is unlikely to harm an
infant. Still, consider to consult you doctor first before you breast-feed a
baby to run off from gaining unwanted side effects.
Exercise caution while using Ibuprofen
in children. Some preparations of Ibuprofen may not be suitable for children
under certain ages. Caution is also needed in the elderly and in people with
impaired kidney, liver, or heart function. Kidney function of anybody that will
take Ibuprofen medicine must always be monitored.
Before you use Ibuprofen, tell your
doctor first whether you have the following conditions:
- Hypertension or High Blood Pressure
- Bleeding Disorders
- Decreased heart function
- Decrease Liver function
- Decrease Kidney function
- Asthma or History of asthma
- History of Allergies
- History of Diseases of the stomach or intestines
Ibuprofen is not to be used in patients
with the following conditions:
- Peptic ulcer or History of Peptic ulcer
- Allergy to Aspirin or to any other ingredients of Ibuprofen
- History of Bronchospasm or narrowing of airways
- History of Rhinitis or inflammation of the nasal membranes
Follow exactly from your doctor’s direction
on using Ibuprofen. You may also ask your doctor, pharmacist, or nurse for
other things which you do not understand.
Take each dose of Ibuprofen with a full
glass of water. Ibuprofen should be taken with food, milk, or an antacid for
reason to lessen stomach upsets.
For additional information on how to
take Ibuprofen, you may ask your doctor. It is important to consult your doctor
first before you make any medical-concern decisions.
Ibuprofen Dosage
Obtain your Ibuprofen dose from your
doctor. Dosage of Ibuprofen drug may vary from person to person. The following
data are just the usual dosage of Ibuprofen drug.
For the treatment of Rheumatoid
arthritis and Osteoarthritis, the dosage of Ibuprofen is 300 mg, 400mg,
600mg, or 800mg. This dosage of Ibuprofen should be adjusted according to
client response. Full response may not be noted still until two or more week is
past.
For the treatment of Juvenile
arthritis, the dosage of Ibuprofen is 30-70mg/kg per day in three to four
divided doses and 20mg/kg per day may be adequate for mild cases.
For the treatment of Mild to moderate
pain in adult, the dosage of Ibuprofen is 400 mg every 4-6 hours as needed.
For the treatment of Antipyretic in
pediatric with 2-12 years of age, the dosage of Ibuprofen is 5mg/kg if baseline
temperature is 102.5°F (39.1°C) and below 10mg/kg if baseline temperature is
greater than 102.5°F (39.1°C). The maximum daily dose of Ibuprofen is 40mg/kg.
For the treatment of
Primary dysmenorrheal in adult, the dosage of Ibuprofen is 400mg every
4 hour as needed.
For the treatment of Mild to moderate
pain, antipyretic, and dysmenorrheal, the dosage of Ibuprofen is 200mg
every 4-6 hours. This dosage of Ibuprofen may be increased to 400mg if pain or
fever continues. Dosage of Ibuprofen should not exceed 1,200 mg per day.
For the treatment of Pain
and fever in children with 2-11 years of age, the dosage of Ibuprofen
is 7.5mg/kg up to a maximum dose of 30mg/kg per day.
Ibuprofen Side Effects
Side effects of Ibuprofen may include
the following:
- Liver disorders
- Kidney Damage
- Dyspepsia or Indigestion
- Blood disorders
- Disturbances of the gut such as diarrhea, nausea, vomiting, or abdominal pain
- Fluid Retention
- Epidermal Necrolysis
- Bleeding from the stomach or intestine
- Stomach or Duodenal Ulcer
- Headache
- Meningitis
- Rash
- Dizziness
- Allergic reactions such as skin rashes, swelling of the lips, tongue, and throat
Other side effects caused by Ibuprofen
may also occur. Consult your doctor immediately if you experienced the above
given side effects or if you feel anything unusual or bothersome effects.
The following other medicines may
interfere with the work of Ibuprofen or may even worsen the situation:
- Blood thinning or Anti-clothing medicines such as Warfarin. The use of these said products may increase the risk of bleeding from the gut.
- Corticosteroids such as Prednisone. The use of these medicines may increase the risk of side effects such as stomach irritation.
- Amlodipine and other Antihypertensive medicines. Ibuprofen decreases the effects of these medicines.
- Diuretics, ACE inhibitors or Ciclosporin. Using these products together with Ibuprofen may increase the risk of kidney problems.
- Other NSAIDs medicines. Taking nay other NSAIDs medicines with Ibuprofen may increase the risk of side effects.
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